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超声波循环塑性在晚期玻璃眼:中期成功,预测失败和并发症的预测因素
Faisal A Almobarak1,2, Ahmed Alrubean1, Waleed K Alsarhani1,3,4
1Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
European journal of ophthalmology
|March 1, 2024
概括
超声波循环整形 (UCP) 在晚期绿眼病患者中有效降低眼内压力 (IOP),但中期成功率中等. 较高的基线内血压和先前的玻璃眼手术预测了更高的失败风险.
科学领域:
- 眼科医生 眼科 眼科
- 视光眼管理 视光眼管理
- 手术干预 手术干预
背景情况:
- 晚期玻璃眼瘤对眼内压力 (IOP) 控制构成重大挑战.
- 目前对晚期青光瘤的治疗选择存在局限性,需要评估替代性手术方法.
研究的目的:
- 评估晚期绿眼病患者的超声波循环形成术 (UCP) 中期成功率.
- 确定与UCP相关的失败和常见并发症的预测因素.
主要方法:
- 分析了接受UCP的晚期玻璃眼患者的研究队列.
- 关键的结果指标包括IOP,青光眼药物的数量和并发症发生率.
- 成功的定义是特定的内皮视力降低和范围,没有危及视力的并发症. 考克斯回归确定了失败预测因素.
主要成果:
- 平均IOP和药物计数在12个月和24个月后显著下降UCP (p <0.01).
- 中期成功率在12个月后为66.2%,在24个月后为72.4%.
- 较高的基线IOP和先前的玻璃眼手术是UCP失败的显著预测因素 (HR=1.10,p=0.03和HR=5.82,分别p<0.01).
结论:
- 超声波循环塑造证明了在降低晚期绿眼病的IOP的有效性.
- 然而,中期成功率是中等的,这表明需要仔细选择患者.
- 前腔反应和白内障进展是最常见的并发症.
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