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Updated: Jul 1, 2025

Development and Functional Characterization of Murine Tolerogenic Dendritic Cells
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矩阵金属蛋白酶-8通过核因子kappa-B p65/β-catenin通路调节晚期多微生物败血症中的树突细胞耐受性

Zhong-Qiu Lu1, Chen Zhang1, Lin-Jun Zhao1,2

  • 1Department of Emergency Medicine, The First Affiliated Hospital of Wenzhou Medical University, Fanhai West Road, Ouhai District, Wenzhou 325000, China.

Burns & trauma
|March 1, 2024
PubMed
概括

矩阵金属蛋白酶-8 (MMP8) 驱动了树突细胞 (DC) 中的败血症诱导的免疫耐受性. 减少MMP8可以通过恢复免疫反应来防止败血症致死率和器官功能障碍.

关键词:
树突性细胞 树突性细胞免疫耐受性是一种免疫耐受性.矩阵金属蛋白酶是一种金属蛋白酶.核因子是卡帕-BB.败血症 这是一种败血症.信号通道的信号通道.这是一种β-catenin.

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