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Updated: Jul 1, 2025

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B细胞前体急性淋巴细胞白血病引发干扰素α/β响应在骨髓衍生中干细胞瘤中

Mandy W E Smeets1, Elisabeth M P Steeghs2, Jan Orsel3

  • 1Dept. of Pediatrics, Erasmus MC-Sophia, Rotterdam, The Netherlands; Princess Máxima Center for Pediatric Oncology, Utrecht.

Haematologica
|March 1, 2024
PubMed
概括

介酶体 stromal 细胞 (MSC) 保护白血病细胞,诱导干扰素 (IFN) 基因在MSC中的签名. 在MSC中这种IFN签名不会提高B细胞前体急性淋巴细胞白血病 (BCP-ALL) 的白血病细胞存活率或耐药性.

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