指甲参与结缔组织疾病:流行病学,临床和皮肤镜研究
Azza Ghannem1,2, Anissa Zaouak1,2, Zohra Aydi2,3
1Department of Dermatology, Habib Thameur Hospital, Tunis, Tunisia.
International journal of dermatology
|March 1, 2024
概括
结合组织疾病 (CTD) 中指甲变化很常见,可以使用指甲皮显微镜检测到. 这项技术有助于诊断和监测系统性硬化症,红斑狼和皮肤肌炎等疾病.
科学领域:
- 皮肤病学 皮肤病学
- 类风湿病学 类风湿病学
- 内部医学 内部医学
背景情况:
- 结合性组织疾病 (CTD) 中的指甲变化未得到充分研究.
- 皮肤显微镜提供了一种新的方法来可视化指甲血管性.
研究的目的:
- 描述CTD患者指甲病变的流行病学,临床和皮肤学特征.
- 评估皮肤镜作为CTD中微血管病的诊断工具.
主要方法:
- 在15个月内进行的前性研究.
- 包括被诊断患有全身性硬化症 (SS),全身性红斑狼 (SLE) 和皮肤肌炎 (DM) 的患者.
- 皮肤镜检查指甲和指甲异常的临床评估.
主要成果:
- 在48名患者中,有44名患者观察到指甲受损.
- 在37名患者中检测到皮肤镜异常,在29例病例中 (SS和DM) 检测到"硬质皮肤模式".
- 临床特征包括破碎的皮质,指甲红血和乳;皮肤镜检查显示了与疾病活动和持续时间相关的模式.
结论:
- 在CTD中指甲异常是多样化的,可以在诊断上具有重要意义.
- 爪皮肤镜是检测早期微血管变化的宝贵工具,有助于CTD的诊断和预后.
相关概念视频
01:23Skin Diseases and Disorders
3.8K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
3.8K
01:30Inflammatory Bowel Disease II: Crohn's Disease
244
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
244