重复的肺转移切除术的结果和预后因素
Ryu Kanzaki1, Hirokazu Watari1, Akiisa Omura1
1Department of General Thoracic Surgery, Osaka International Cancer Institute, Osaka, Japan.
Interdisciplinary cardiovascular and thoracic surgery
|March 1, 2024
概括
重复肺转移切除术 (PM) 后的结果表明,手术间隔较长 (>12个月) 与更好的生存率有关. 第三个PM可能有利于某些患有肺转移的患者.
科学领域:
- 手术瘤学手术瘤学
- 胸部外科手术 胸部外科手术
- 癌症转移研究 癌症转移研究
背景情况:
- 重复的肺转移切除术 (PM) 的预后因素尚未得到充分确立.
- 第三个PM后的结果特别没有得到充分的记录.
研究的目的:
- 分析第二次PM患者的结果和预后因素.
- 为了评估第三个PM肺转移的结果.
主要方法:
- 在2000年至2020年期间,对68名经历了重复PM的患者进行了回顾性分析.
- 预后因素的调查,包括转移检测和外科手术方法的间隔.
- 评估第二次和第三次PM程序后的生存率和结果.
主要成果:
- 第一次PM和转移检测之间的较短间隔 (≤12个月) 是第二次PM后无复发和整体存活的不良预后因素.
- 第二次PM后的五年无复发和整体生存率分别为27%和48%.
- 17名患者接受了第三次PM,其中3人实现了3年无病生存.
结论:
- 第一次PM和转移检测之间的间隔>12个月的患者具有有利的结果,并且是第二次PM的良好候选人.
- 第三个PM可能对经过精心挑选的患有复发性肺转移的患者有益.
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