关于世界卫生组织处方指标的综合策略干预:一个准随机试验
Nondumiso B Q Ncube1, Tawanda Chivese, Ferdinand C Mukumbang
1Department of Community and Health Sciences, School of Public Health, University of the Western Cape, Cape Town. nncube@uwc.ac.za.
African journal of primary health care & family medicine
|March 1, 2024
概括
埃斯瓦蒂尼关于合理使用药物的研究发现,处方审计和反干预并没有改善处方实践. 建议采取多方面的策略,以更好地使用药物,并对抗抗菌素耐药性.
科学领域:
- 公共卫生 公共卫生
- 药理学 药理学是指药理学的学科.
- 医疗保健服务研究 医疗服务研究
背景情况:
- 不合理的药物使用是一个重大的全球挑战,有助于抗菌素耐药性.
- 在中低收入环境中观察到不合理的处方做法的高患病率.
研究的目的:
- 评估埃斯瓦提尼公共医疗机构的处方做法.
- 评估处方审计和反干预,结合小组教育对处方指标的影响.
主要方法:
- 这是一项集群类随机对照研究,从2016年到2019年在斯瓦西尼的32个医疗机构进行.
- 使用的世界卫生组织/合理使用药物国际网络 (WHO/INRUD) 处方指标.
- 干预涉及6个月的审计,反和教育;在基线,干预后和6个月的随访期间收集的数据.
主要成果:
- 处方药和注射用药的合理处方标准在基线达到.
- 在干预组和对照组中,抗生素使用超过了50%.
- 干预后和随访时的组之间没有发现任何处方指标的显著差异,即使在调整后也是如此.
结论:
- 测试的干预措施 (处方审计,反和教育) 在这个环境中没有改善合理的处方.
- 建议采取多方面的策略,包括加强药房和治疗委员会以及全面的药物使用监测.
- 解决不合理的药物使用对于打击抗菌素耐药性至关重要.
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