儿童中自闭症和神经发育障碍的风险 气管切除术和呼吸机儿童
Sarah A Sobotka1, Emma Lynch1, Chuanhong Liao2
1Section of Developmental and Behavioral Pediatrics, Department of Pediatrics, The University of Chicago, Chicago, Illinois, USA.
在严重疾病后需要在家进行侵入性机械通风 (IMV) 的儿童面临自闭症谱系障碍 (ASD) 和智力障碍 (ID) 的高风险. 这项研究发现,67%的儿童表现出这些发育问题的迹象.
科学领域:
- 儿科神经学 儿科神经学
- 发育儿科 发育儿科
- 新生儿科学 新生儿科学
背景情况:
- 患有急性疾病而需要出院后入侵性机械通风 (IMV) 的婴儿存在神经发育延迟的高风险.
- 之前对极度早产婴儿的研究表明,智力障碍 (ID) 和自闭症谱系障碍 (ASD) 的比例很高.
- 医院出院后IMV的儿童的神经发育结果尚未得到充分确立.
研究的目的:
- 为了确定神经发育障碍的风险,包括ASD和ID,在医院出院后需要IMV的儿童.
- 评估这个脆弱的儿科群体的认知,社会和沟通能力的发展.
主要方法:
- 一组18名患有退院后IMV的儿童被跟踪了一年.
- 神经发育的评估包括卡普特尺度 (CAT/CLAMS),PEDI-CAT和MCHAT-R.
- 用DSM-V标准和专家共识评估ASD和ID的发育和行为儿科医生.
主要成果:
- 退院一年后,患者的中位年龄为23个月.
- 83%的孩子是过早生育的幸存者.
- 67%的儿童高度怀疑ASD和/或演变的ID,平均发育系数从49.5到66.5.5不等.
结论:
- 与以前的早产婴儿队伍相比,在家中感染IMV的儿童患ASD和ID的风险更高.
- 这项研究强调了对这一群体进行更密切的监测和早期干预的需要.
- 需要进行更大规模的随访研究来证实这些发现.
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