短期血管对春季和秋季的反应 节日时间的变化
Dara Al-Bakry1, Chloe E Athaide1, Rishiga Pathmarajan1
1Department of Kinesiology and Health Sciences, University of Waterloo, Waterloo, Canada.
概括
日光节约时间 (DST) 的变化并没有改变健康成年人的心血管功能或睡眠质量. 这项研究没有发现DST过渡后观察到心血管风险增加的生理基础.
科学领域:
- 心血管生理学心血管生理学
- 时间生物学 时间生物学
- 公共卫生 公共卫生
背景情况:
- 节约日光时间 (DST) 涉及两年一次的时钟变化,流行病学链接在春班后增加急性心肌梗塞风险.
- 将DST过渡与心血管事件联系起来的生理机制尚不清楚.
- 鉴于关于废除DST的公共卫生辩论,了解DST对心血管功能的影响至关重要.
研究的目的:
- 在健康的成年人中研究秋季和春季的DST变化对心血管的短期影响.
- 测试这个假设,即春季的夏季时间变化会急剧增加中枢动脉硬度 (通过脉冲波速度测量).
主要方法:
- 21名健康成年人在春季和秋季DST过渡之前和之后进行了评估.
- 测量包括中央,手臂和半径脉冲波速,动脉增大指数,心率和平均动脉压力.
- 睡眠质量和认知功能也通过问卷和标准化任务进行了评估.
主要成果:
- 在秋季或春季DST过渡后,在任何心血管变量 (脉冲波速度,增强指数,心率,平均动脉压) 中没有发现显著变化.
- 睡眠质量和认知功能也保持不变.
- 所有测试的参数都显示P > 0.05,表明没有统计学上显著的影响.
结论:
- 这项研究没有发现任何证据表明DST变化对健康成年人的心血管结果或相关生理标志物有严重影响.
- 这些发现突出了流行病学观察增加心血管风险和可证明的生理变化之间的差距.
- 需要进一步进行大规模的多站点研究,以阐明DST相关心血管事件背后的机制.
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