类风湿性关节炎和分娩期间的心血管并发症:美国的一项住院分析
Salman Zahid1, Mohamed S Mohamed2, Aardra Rajendran3
1Knight Cardiovascular Institute, Oregon Health and Science University, Portland, OR, USA.
European heart journal
|March 1, 2024
概括
患有类风湿性关节炎 (RA) 的妇女在分娩期间面临更高的产周心血管并发症风险,包括产前和心肌病. 这些患者15年内心代谢风险因素也增加.
科学领域:
- 产科和妇科 产科和妇科
- 类风湿病学 类风湿病学
- 心脏病学 心脏病学
背景情况:
- 类风湿性关节炎 (RA) 与产科和长期心血管风险的增加有关.
- 在分娩期间评估RA和急性心血管并发症之间的特定关联至关重要.
研究的目的:
- 评估类风湿性关节炎 (RA) 与急性心血管 (CV) 并发症在分娩期间住院期间的关联.
主要方法:
- 利用了国家住院患者样本 (2004-2019) 的数据.
- 使用ICD-9/ICD-10代码确定了分娩住院和RA诊断.
主要成果:
- 关节炎患者 (0.1%的分娩) 年龄较大,并患有高血压,糖尿病,肥胖和脂质失调等并发病率较高.
- 调整后的分析显示,RA是孕前,周周心肌病,心律失常,急性损伤和静脉血栓栓塞的独立危险因素.
- 从2004年到2019年,在RA患者中观察到肥胖,妊娠期糖尿病和急性心血管并发症的增加趋势.
结论:
- 怀孕中患有RA的孕妇在分娩期间表现出患有妊娠前,产周心肌病,心律失常,急性损伤和静脉血栓栓塞的风险较高.
- 在15年的时间里,心脏代谢风险因素在RA的孕妇中显著增加.
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