自我报告的COVID-19感染后的日常功能
Theodore J Iwashyna1,2,3,4, Valerie A Smith5,6,7, Sarah Seelye1
1VA Center for Clinical Management Research, Ann Arbor VA, Ann Arbor, Michigan.
JAMA network open
|March 1, 2024
概括
许多退伍军人在疫情期间经历了日常功能减少,无论COVID-19感染状况如何. 需要对更大样本进行进一步的研究,以确认这些关于长期COVID影响的发现.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 纵向研究 纵向研究
背景情况:
- 评估COVID-19对日常生活的长期影响至关重要.
- 了解感染后的功能变化,可以为恢复和支持策略提供信息.
研究的目的:
- 为了调查COVID-19对退伍军人18个月后感染的日常功能的影响.
- 为了比较具有和没有COVID-19病史的退伍军人之间的功能结果.
主要方法:
- 一项包括186名患有COVID-19的退伍军人和186名来自美国退伍军人事务局的匹配对照的队列研究.
- 针对性试验的仿真原则被用于基于39个感染前变量进行匹配.
- 权重后勤和线性回归分析了自我报告的日常运作的差异.
主要成果:
- 较高比例的COVID-19幸存者 (44.9%) 报告功能减弱相比对照 (35.3%) 感染后18个月.
- 在COVID-19感染和疲劳,疼痛,日常生活限制,流动性,就业或生活质量之间没有发现显著的关联.
结论:
- 许多退伍军人报告说,在疫情期间,无论他们是否感染了COVID-19,日常功能都显著下降.
- 这项研究强调了大流行对身体运作的广泛影响,需要对更大的队列进行进一步调查.
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