在多巴胺耗尽期间,M4-受体胆固醇信号在直接通路条状投射神经元中的作用

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V H Avilés‐Rosas1, E A Rendón‐Ochoa2, T Hernández-Flores1

  • 1Instituto de Fisiología Celular, División de Neurociencias, Universidad Nacional Autónoma de México, Ciudad de México, México.

Synapse (New York, N.Y.)
|March 1, 2024
PubMed
概括

肌肉M4受体 (M4R) 在多巴胺缺乏的神经元中发出信号,对于帕金森症研究至关重要,涉及Cdk5通路. M4R激活改变流和蛋白质水平,Cdk5在健康和疾病状态中起着关键作用.

关键词:
在Ca2+-通道中.在Cdk5dk5这是一个PP-1PP-1PP-1PP-1.乙烯基胆是一种直接通路 条状投影神经元 神经元多巴胺是多巴胺的一种.肌肉类M4受体的受体.帕金森主义是帕金森主义.

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