叶绿素与成人的骨矿物质密度和骨矿物质含量相关:基于人口的横截面研究
Lin Li1, Xuekui Liu2, Xia Zhang3
1Graduate School of Bengbu Medical College, Bengbu, Anhui, China.
PloS one
|March 1, 2024
概括
这项研究发现,在美国成年人中,甲暴露与骨矿物质密度 (BMD) 和骨矿物质含量 (BMC) 之间存在"V"形联系. 长时间暴露于形式可能会影响骨健康,特别是在女性和老年人中.
科学领域:
- 环境健康 环境健康
- 骨的新陈代谢 骨的新陈代谢
- 毒理学 毒理学 毒理学
背景情况:
- 骨矿物质密度 (BMD) 对于评估骨质疏松风险至关重要.
- 挥发性有机化合物 (VOCs) 对骨的影响还没有得到充分的研究.
- 形式暴露与骨健康之间的具体关系尚不清楚.
研究的目的:
- 调查甲暴露与BMD/BMC之间的关联.
- 分析这些关系在不同的骨部位 (脊椎和股骨).
主要方法:
- 利用了2,553名美国成年人的数据 (NHANES,2009-2020).
- 采用了t测试和多线性回归模型.
- 在脊椎和大腿部区域对BMD/BMC进行了评估.
主要成果:
- 在未经调整的模型中,观察到甲暴露和BMD/BMC之间的"V"形相关性.
- 对沃德三角形和L4 BMD/BMC 进行了负相关性.
- 调整后的模型显示,L4 BMC和甲暴露之间存在主要负相关性,特别是在女性和65-80岁的人群中.
结论:
- 在美国成年人中,甲暴露与股骨/脊椎BMD/BMC之间存在显著的"V"形关联.
- 长时间暴露于形式可能会改变骨矿物质密度和含量.
- 研究结果表明,暴露于环境中的形式对骨健康有潜在的风险.
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