肺外结核患者的上腺形态和皮质功能:对抗结核治疗的反应
Bashir Ahmad Laway1, Bhanu Pratap Singh Blouria2, Rafi Ahmad Jan2
1Department of Endocrinology, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, Kashmir, India, drlaway@gmail.com.
Archives of endocrinology and metabolism
|March 1, 2024
概括
肺外结核 (EPTB) 与上腺扩大和皮质醇水平降低有关. 对EPTB的治疗使上腺的大小正常化,并改善患者的皮质醇功能.
科学领域:
- 内分泌学 在内分泌学.
- 传染性疾病 传染性疾病
- 放射学 放射学是一门学科.
背景情况:
- 结核病患者的上腺皮质功能和上腺腺体大小变化被注意到.
- 在肺外结核 (EPTB) 治疗期间,上腺形态的动态变化存在有限的研究.
研究的目的:
- 为了研究EPTB患者上腺体大小和功能的变化.
- 将EPTB患者的上腺形态和皮质醇水平与治疗前后的健康对照进行比较.
主要方法:
- 对37名EPTB患者和37名对照进行前性研究.
- 通过血清皮质醇水平 (基线和ACTH刺激) 评估上腺功能.
- 使用计算机断层扫描 (CT) 扫描评估的上腺体大小.
主要成果:
- 与对照组相比,EPTB患者的基线和ACTH刺激的皮质醇水平显著降低.
- 在治疗前,EPTB患者的上腺长度和厚度较大.
- 在抗结核治疗后,皮质醇水平增加,上腺的大小正常化.
结论:
- 患有EPTB的患者出现上腺扩大和皮质醇生产受损.
- 抗结核治疗导致皮质醇水平的显著改善和上腺体大小的正常化.
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