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Updated: Jul 1, 2025

Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes
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Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes

Published on: April 4, 2025

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DNA聚合酶 λ Loop1 变体在非同类末端连接中产生了意想不到的功能获取能力

Andrea M Kaminski1, Kishore K Chiruvella2, Dale A Ramsden2

  • 1Genome Integrity and Structural Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, 111 TW Alexander Dr., Bldg 101, Research Triangle Park, NC 27709, USA.

DNA repair
|March 1, 2024
PubMed
概括

DNA聚合酶lambda和mu是DNA修复的关键. 一种经过修改的DNA聚合酶兰巴达意外获得了DNA修复能力,突出了Loop1区域在DNA双链断裂修复中的关键作用.

关键词:
DNA双链断裂修复的修复方法DNA聚合酶 Mu 是一个分子.在DNA聚合酶兰巴达.循环1 一个循环1不同类型的末端连接突触 (Synapsis) 是一个突触.

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