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Updated: Jul 1, 2025

Glomerular Outgrowth as an Ex Vivo Assay to Analyze Pathways Involved in Parietal Epithelial Cell Activation
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殖民地刺激因子-1受体驱动在焦点细分型结核硬化中球体表皮细胞激活

Josep M Cruzado1, Anna Manonelles2, Sandra Rayego-Mateos3

  • 1Department of Nephrology and Transplantation, Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), Hospitalet de Llobregat, Barcelona, Spain; Department of Nephrology, Hospital Universitari Bellvitge, Barcelona, Spain; Department of Clinical Sciences, University of Barcelona, Barcelona, Spain.

Kidney international
|March 1, 2024
PubMed
概括

殖民地刺激因子-1受体 (CSF-1R) 的激活驱动焦点细分样硬化症 (FSGS) 中的上皮细胞 (PEC) 的激活. 抑制CSF-1R显示出治疗FSGS病的治疗潜力.

关键词:
在CSF-1R中使用CSF-1R.这些都是FSGS,FSGS,FSGS.一个PECs的PECs.葡萄细胞 (podocytes) 是一个细胞.

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