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Updated: Jul 1, 2025

Modeling Paracrine Noncanonical Wnt Signaling In Vitro
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Published on: December 10, 2021

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可溶性 纹相关蛋白质促进外体介导的Wnt再分泌

Thi Hong Nguyen Tran1,2,3, Ritsuko Takada1,2, Elena Krayukhina4,5,6

  • 1Exploratory Research Center on Life and Living Systems (ExCELLS), National Institutes of Natural Sciences, 5-1 Higashiyama, Myodaiji-cho, Okazaki, Aichi, 444-8787, Japan.

Communications biology
|March 1, 2024
PubMed
概括

像sFRP2这样分泌的状相关蛋白 (sFRPs) 通过外体增强了Wnt蛋白通过外体的运输. 这涉及Wnt与sFRP2的二分化,促进Wnt在细胞表面积累的肝硫酸蛋白糖 (HSPGs) 进行再分泌.

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