用Angiojet治疗急性动脉闭塞的药用机械血栓切除术:在结果和结局中进行的一项前性研究
Rafael de Athayde Soares1, Ana Beatriz Campelo Campos1, Matheus Veras Viana Portela1
1Division of Vascular and Endovascular Surgery, Hospital do Servidor Público Estadual de São Paulo, Sao Paulo, Brazil.
Vascular
|March 2, 2024
概括
使用Angiojet治疗急性四肢缺血症 (ALI) 的药用机械血栓切除术 (PMT) 是有效的. 然而,使用>150周期/秒与急性损伤和死亡率的增加有关.
科学领域:
- 血管外科 血管外科
- 干预心脏病学 干预心脏病学
- 血管内治疗疗法 血管内疗法
背景情况:
- 急性四肢缺血 (ALI) 是一种需要及时干预的危急情况.
- 使用像Angiojet这样的设备的药用机械血栓切除术 (PMT) 提供了一种微创治疗选择.
研究的目的:
- 评估用Angiojet PMT治疗的ALI患者的结局.
- 评估Angiojet循环次数/秒对患者结果的影响.
主要方法:
- 92名接受PMT的ALI患者的前性连续队列研究.
- 患者分为两组:第一组 (>150循环/秒) 和第二组 (<150循环/秒).
主要成果:
- 总体死亡率为15.1%. 第1组的死亡率比第2组 (9.3%) 高 (16.1%).
- 截肢救援率为85% (第一组) 和95.7% (第二组).
- 较高的周期 (>150/s),COVID-19和急性损伤 (AKI) 与死亡率有关.
结论:
- 与Angiojet一起的PMT对ALI是安全有效的.
- 使用>150周期/秒与增加的AKI和死亡率相关,可能是由于血液溶解和血栓负担.
- AKI,>150周期/秒,和COVID-19是术后死亡率的关键预测指标.
相关概念视频
Treatment for Pulmonary Arterial Hypertension: Prostacyclin Receptor Agonists
613
Prostacyclin receptor agonists are a class of therapeutic agents integral to managing pulmonary arterial hypertension (PAH). These drugs operate by mimicking the action of prostaglandin I2, or PGI2, a naturally occurring compound in the body.
These agonists bind to the IPR receptor situated on the plasma membrane of the pulmonary artery smooth muscle cells. This binding triggers a cascade of reactions known as the GS-AC-cAMP-PKA pathway. This pathway results in the relaxation of smooth muscle...
These agonists bind to the IPR receptor situated on the plasma membrane of the pulmonary artery smooth muscle cells. This binding triggers a cascade of reactions known as the GS-AC-cAMP-PKA pathway. This pathway results in the relaxation of smooth muscle...
613
Acute Coronary Syndrome IV: Interprofessional Care
522
IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
522
Peripheral Artery Disease III: Interprofessional Care
655
Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
655
Venous Thrombosis III: Interprofessional Care
482
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
482
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
748
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
748


