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Updated: Jul 1, 2025

A G-quadruplex DNA-affinity Approach for Purification of Enzymatically Active G4 Resolvase1
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A G-quadruplex DNA-affinity Approach for Purification of Enzymatically Active G4 Resolvase1

Published on: March 18, 2017

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通过G4 - 连接物结合的寡核酸,对个体G4 DNA结构进行选择性结合和稳定

Andreas Berner1, Rabindra Nath Das2, Naresh Bhuma2

  • 1Department of Medical Biochemistry and Biophysics, Umeå University, Umeå 901 87, Sweden.

Journal of the American Chemical Society
|March 2, 2024
PubMed
概括

研究人员开发了一种新方法,使用与指导性寡核酸结合的G4连接体专门针对个体G四重复 (G4) DNA结构. 这一战略克服了G4DNA选择性的挑战,为研究和潜在的治疗提供了新的工具.

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