在euthyroid Graves' ophthalmopathy中对眼表面和梅博米腺的评估
Kenneth Ka Hei Lai1,2, Xulin Liao1, Fatema Mohamed Ali Abdulla Aljufairi1,3
1Department of Ophthalmology and Visual Sciences, Hong Kong Eye Hospital, The Chinese University of Hong Kong, 147K Argyle Street, Kowloon, Hong Kong, Hong Kong SAR.
International ophthalmology
|March 2, 2024
概括
与健康个体相比,Euthyroid Graves眼科 (EGO) 患者的眼球表面疾病和梅博米腺脱落明显增加. 干眼症状很常见,但并非由于水性缺乏,因此需要进一步研究与EGO相关的干眼机制.
科学领域:
- 眼科医生 眼科 眼科
- 内分泌学 在内分泌学.
- 眼睛表面疾病 眼睛表面疾病
背景情况:
- 甲状腺外科格雷夫斯眼科 (EGO) 是甲状腺眼病的一种特定亚型.
- 了解EGO眼表面和梅博米腺的变化对于患者管理至关重要.
研究的目的:
- 评估EGO患者的眼表面和梅博米腺的变化.
- 为了将这些发现与年龄和性别匹配的健康对照进行比较.
主要方法:
- 一项涉及34名EGO患者和34名对照者的横截面研究.
- 使用前段检查,角膜学和美图学.
- 评估了眼睛表面疾病指数 (OSDI).
主要成果:
- 在EGO患者中,OSDI得分更高,梅博姆腺脱落增加,部分眼增加.
- 在EGO患者中,受影响较严重的眼睛显示出角膜染色,眼异常和美腺功能受损 (插入,表达能力,美质量).
- 眼半径高度,脂质层厚度和非侵入性眼破裂时间在EGO患者和对照者之间是可比的,尽管眼半径高度与外眼相对应.
结论:
- 与健康人相比,EGO患者的眼睛表面并发症和梅博米腺功能障碍更大.
- 很大一部分EGO患者报告眼睛干燥症状,主要是没有明显的水性缺陷.
- 需要进一步调查以阐明导致EGO眼睛干燥的具体机制.
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