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Updated: Jul 1, 2025

Single-cell Resolution Fluorescence Live Imaging of Drosophila Circadian Clocks in Larval Brain Culture
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Single-cell Resolution Fluorescence Live Imaging of Drosophila Circadian Clocks in Larval Brain Culture

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灵活的MEA揭示了对时钟基因在多巴胺动力学中的作用的新见解

Bingchen Wu1,2, Elisa Castagnola1,3, Colleen A McClung4

  • 1Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, 15213, USA.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|March 2, 2024
PubMed
概括

时钟基因调节多巴胺合成. 新的多电极阵列揭示了缺乏时钟基因的小鼠中多巴胺水平的变化,影响神经活动和昼夜节律.

关键词:
在PEDOT/CNT.慢性多巴胺传感感应慢性电生理学 慢性电生理学昼夜节律 昼夜节律灵活的MEAs可以灵活使用.

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相关概念视频

Circadian Rhythms and Gene Regulation02:19

Circadian Rhythms and Gene Regulation

The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and Erwin Bünning, discovered the existence of circadian rhythm in Drosophila melanogaster. However, the internal molecular mechanisms behind the circadian clock remained a mystery until 1984, when Jeffrey C. Hall, Michael Rosbash, and Michael W. Young discovered the expression of the Per gene oscillating over a 24-hour cycle. In subsequent...
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