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在神经元细胞模型中,MLKL过度表达导致Ca2+和代谢静态变异

Sathyaseelan S Deepa1, Nidheesh Thadathil2, Jorge Corral3

  • 1Department of Biochemistry and Physiology, University of Oklahoma Health Sciences Center, OK, USA; Center for Geroscience and Healthy Brain Aging, University of Oklahoma Health Sciences Center, OK, USA; Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.

Cell calcium
|March 2, 2024
PubMed
概括

在神经元中积累的死亡因子MLKL可能会导致大脑衰老. 在神经细胞中过度表达MLKL而不会导致死亡,诱导了细胞衰老的特征,包括改变的和代谢失调.

关键词:
衰老的衰老 衰老的衰老是一种乳酸盐是一种乳酸盐.MLKL 没有使用代谢过程中的代谢.线粒体中的线粒体.尸体灭 (Necroptosis) 是一种死亡的过程.神经元神经元是一个神经元.

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