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在实验近视中,纤毛体中 lncRNA 和 mRNA 档案的表征

Shanshan Wu1, Jiawen Hao2, Dadong Guo3

  • 1Department of Ophthalmology, West China Hospital, Sichuan University, Chengdu, 610041, China; Shandong University of Traditional Chinese Medicine, Jinan, 250002, China.

Experimental eye research
|March 2, 2024
PubMed
概括

研究人员使用透镜诱导近视 (LIM) 动物模型探索了状体在近视发展中的作用. 研究结果显示,纤毛体发生了显著的分子变化,这表明它参与了近视的进展.

关键词:
体是一种体.这是一个LncRNARNA.近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近在RNA-Seqq.它们是mRNARNA.

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In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA (lncRNA)...