OPTN/SRTR 2022 年度数据报告:心脏
Monica M Colvin1, Jodi M Smith2, Yoon Son Ahn3
1Scientific Registry of Transplant Recipients, Hennepin Healthcare Research Institute, Minneapolis, MN; Department of Cardiology, University of Michigan, Ann Arbor, MI.
概括
成人和儿童的心脏移植数量正在上升,存活率有所改善. 然而,儿科移植率已经下降,婴儿移植前死亡率仍然很高.
科学领域:
- 心血管医学 心血管医学
- 移植手术 移植手术
- 公共卫生趋势 公共卫生趋势
背景情况:
- 自2011年以来,美国心脏移植的数量显著增加.
- 儿科和成人心脏移植候选人数量也大幅增加.
- 有利的捐赠者趋势包括增加心脏恢复和循环死亡后的采购.
研究的目的:
- 分析2011年至2022年美国儿科和成人候选人心脏移植的趋势.
- 评估移植率,移植前死亡率和移植后生存率的变化.
- 评估捐赠者趋势对心脏移植结果的影响.
主要方法:
- 分析2011年至2022年全国心脏移植数据.
- 在儿童和成人群体中计算每100个患者年的移植率.
- 移植前和移植后的死亡率和生存率的评估.
主要成果:
- 在2011年至2022年期间,成人心脏移植增加了85.8%,儿童心脏移植增加了31.7%.
- 成人移植率达到每100个患者年122.5的峰值,而儿科移植率降至104.2.2.
- 移植前的死亡率在两组中都显著下降,但在婴儿 (<1岁) 中仍然很高.
结论:
- 虽然整体心脏移植正在增加,生存率更好,但儿科移植率的下降令人担忧.
- 需要继续努力,以解决最年轻的儿科候选人的高移植前死亡率.
- 积极的捐赠者趋势支持心脏移植计划的持续扩张.
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