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OPTN/SRTR 2022 年度数据报告:肺部
Maryam Valapour1, Carli J Lehr2, David P Schladt3
1Scientific Registry of Transplant Recipients, Hennepin Healthcare Research Institute, Minneapolis, MN; Department of Pulmonary Medicine, Respiratory Institute, Cleveland Clinic, Cleveland, OH.
概括
肺部移植数量在2022年上升,这是肺部分配得分的最后一年. 整体而言,移植率有所上升,但接入和存活率因患者人口统计学而异.
科学领域:
- 肺部病理学 肺部病理学
- 移植手术 移植手术
- 公共卫生 公共卫生
背景情况:
- 美国每年肺移植的数量自COVID-19大流行以来首次增加.
- 2022年标志着使用肺部分配分数 (LAS) 进行器官分配的最后一个完整日历年.
- 在2023年3月,随着复合分配分数 (CAS) 的引入,政策发生了重大转变.
研究的目的:
- 报告2022年美国肺移植活动情况.
- 分析肺移植率,等待列表时间和生存结果的趋势.
- 突出肺移植获取和结果的人口差异.
主要方法:
- 分析2022年起的国家肺移植数据.
- 对肺移植候选人等候名单指标的审查.
- 检查移植前和移植后的死亡率和生存率.
主要成果:
- 与之前的流行病年相比,2022年肺移植人数增加.
- 移植率显示了长达十年的增长,有显著的人口差异.
- 超过50%的候选人在3个月内接受了移植,近75%在一年内接受了移植.
- 移植前死亡率保持稳定,在上市后的一年内约为13%.
- 移植后的存活率稳定,但在不同患者群体中显示出差异性.
结论:
- 在2022年,肺移植数量出现了复苏.
- 虽然整体移植率和存活率稳定,但在各种患者人口统计学中仍然存在显著差异.
- 从LAS到CAS的过渡可能会影响未来的移植分配和结果.
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