根据全国数据库的数据,COVID-19住院的喘患者的临床趋势:一项观察性研究
Akinari Tsukada1, Junko Terada-Hirashima2, Jin Takasaki2
1Department of Respiratory Medicine, National Center for Global Health and Medicine, Tokyo, 162-8655, Japan. atsukada@hosp.ncgm.go.jp.
BMC pulmonary medicine
|March 2, 2024
概括
住院患有COVID-19 (冠状病毒病2019) 的喘患者没有面临更高的死亡率或机械通风风险. 然而,年龄和未接种疫苗等因素增加了这个群体的严重COVID-19风险.
科学领域:
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 喘患者中COVID-19的临床特征在很大程度上是未知的.
- 这项研究调查了喘与COVID-19严重性和死亡率的关联.
研究的目的:
- 为了检查喘和COVID-19严重程度和死亡风险之间的关联.
- 为了确定喘患者严重COVID-19结局的危险因素.
主要方法:
- 来自日本COVID-19注册数据库 (2020年1月至2022年12月) 的数据分析.
- 包括72582名住院COVID-19患者,其中3731人被诊断患有喘.
- 多变量逻辑回归来评估喘作为死亡和机械通风的风险因素.
主要成果:
- 从2020年1月到2021年6月,喘与增加的死亡率 (OR0.837) 或侵入性机械通风 (OR1.084) 没有显著的关联.
- 在2021年7月之后进行的分析中观察到类似的结果.
- 年龄,BMI,CKD,未接种疫苗和高血压等因素增加了喘患者机械通风风险.
结论:
- 患有喘的患者由于COVID-19而没有增加死亡或机械通风的风险.
- 由于年龄,BMI,慢性病和未接种疫苗等因素,喘患者面临更高的严重COVID-19风险.
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