肥胖对呼吸机相关肺炎的影响,这是美国全国性的研究
Mohamad El Labban1, Michella Abi Zeid Daou2, Hiba Smaily3
1Assistant Professor Mayo Clinic College of Science and Medicine-Internal Medicine, Mayo Clinic Health System, Mankato, MN, USA.
肥胖并没有显著增加呼吸机相关肺炎 (VAP) 患者的死亡率或气管切除率. 肥胖患者在医院住院时间较长,但其他情况的结果相似.
科学领域:
- 关键护理医学 关键护理医学
- 肺部病理学 肺部病理学
- 肥胖医学 肥胖医学
背景情况:
- 呼吸器相关的肺炎 (VAP) 是重症患者死亡的重要原因.
- 肥胖是一种普遍的疾病,可能会对VAP结果产生影响.
研究的目的:
- 为了研究肥胖和成年患者诊断出VAP之间的关系.
- 为了确定肥胖是否是不良VAP结果的独立风险因素.
主要方法:
- 国家住院样本 (NIS) 数据库 (2017-2020年) 的回顾性分析.
- 包括患有VAP的成年患者,根据ICD-10代码对肥胖状况进行分类.
- 多变量后勤回归分析以评估死亡率,气管切除术,停留时间和患者费用,并调整混因素.
主要成果:
- 这项研究包括3832名VAP患者;395人患有肥胖症.
- 肥胖与糖尿病,高血压和睡眠呼吸暂停等并发病率较高有关.
- 在肥胖和非肥胖的VAP患者之间,死亡率 (10%与8.5%) 或气管切除率没有统计学上显著的差异.
- 肥胖患者住院时间更长.
- 在任何一组的VAP护理中都没有发现种族差异.
结论:
- 肥胖不是VAP患者死亡率增加的独立风险因素.
- 虽然肥胖患者可能会经历更长时间的住院治疗,但他们的整体VAP结果与非肥胖个体相似.
- 进一步的研究可能会探索肥胖VAP患者的特定管理策略.
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