视觉幻觉,功能和疾病过程中的自杀倾向之间的关系:在第一发精神病的10年随访研究
Isabel Kreis1, Kristin Fjelnseth Wold2, Gina Åsbø3
1NORMENT, Institute of Clinical Medicine, University of Oslo, Oslo, Norway. i.v.kreis@medisin.uio.no.
Schizophrenia (Heidelberg, Germany)
|March 2, 2024
概括
精神病中的视觉幻觉与更糟糕的功能和更高的症状严重程度有关. 早期的视觉幻觉预测了整个疾病过程中反复的自杀企图.
科学领域:
- 精神病学是一个精神病学.
- 神经科学是一个神经科学.
- 临床心理学 临床心理学
背景情况:
- 精神病中的视觉幻觉 (VH) 尚未得到充分研究.
- 现有研究将VH与疾病严重程度增加,功能障碍和自杀倾向联系起来.
- 缺乏关于精神病中VH的长期纵向数据.
研究的目的:
- 调查视觉幻觉对第一次精神病发作中的功能和自杀倾向的长期影响.
- 确定VH和疾病严重程度之间的关联是否是状态或特征现象.
- 检查VH的轨迹及其与疾病标志物的关系超过10年.
主要方法:
- 对184名患有第一发精神病的个人进行了前性纵向研究.
- 在基线和10年后期使用临床访谈和问卷进行评估.
- 根据对视觉幻觉的终身经验分类的参与者:VH+/+ (早期/基线),VH-/+ (晚期发病),VH-/- (从未).
主要成果:
- 早期的VH (VH+/+) 与功能不佳,症状严重程度更高,早期发病,以及在基线时更多的自杀企图有关.
- 晚期发作的VH (VH-/+) 与随访时功能较差和症状严重程度较高有关.
- 早期的VH (VH+/+) 一贯与整个疾病过程中的多次自杀企图有关.
结论:
- 视觉幻觉与功能障碍和更严重的症状严重性有关,特别是在短期内.
- 精神病早期出现的视觉幻觉是反复自杀企图的重要风险指标.
- 随着时间的推移,监测视觉幻觉的发展对于管理精神病至关重要.
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