在患有产前阿片类药物暴露的儿童中,2岁时出现的神经行为问题
Nimrah Baig1,2, Qin Sun3, Chunyan Liu3
1Perinatal Institute, Division of Neonatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. nimrah.a.baig@osfhealthcare.org.
概括
在儿童中产前阿片类药物暴露可能导致行为问题. 较低的运动分数和特定的排放计划与外部化问题有关,而某些药物有助于正常发育.
科学领域:
- 儿科 儿科 儿科
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
背景情况:
- 产前阿片类药物暴露是影响儿童发育的日益关注的问题.
- 了解影响这些儿童行为结果的因素对于早期干预至关重要.
研究的目的:
- 在产前阿片类药物暴露的儿童中,识别与儿童行为检查清单 (CBCL) 上的边界或临床范围得分相关的因素.
主要方法:
- 追溯性研究涉及94名儿童在产前接触过阿片类药物.
- 儿童在2岁时使用CBCL进行评估.
主要成果:
- 30%的儿童表现出边界/临床CBCL得分,其中27%显示出外部化问题.
- 降低贝利-III电机分数和排放与与外部化问题相关的安全计划.
- 对新生儿阿片类戒断综合征 (NOWS) 的药物治疗和用克洛尼丁或费诺巴比塔尔的治疗与所有测量标准的正常CBCL得分有关.
结论:
- 包括运动发育和护理安排在内的特定因素与暴露在阿片类药物中的儿童的行为挑战有关.
- 药理干预可以在缓解行为问题方面发挥作用.
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