口腔内镜性肌肉切除:对实践和不良事件的两中心回顾性研究
C Van Severen1, S Koch2, J Faure2
1Centre Hospitalier universitaire de Liège, Gastroenterology and Hepatology, Liège, Belgium.
Acta gastro-enterologica Belgica
|March 3, 2024
概括
口腔内镜肌切除术 (POEM) 是对食道运动障碍的安全有效治疗方法. 这项研究发现两所大学中心的疗效和安全性结果相似,抗生素预防对感染率没有影响.
科学领域:
- 胃肠病学 胃肠病学
- 最少侵入性的手术
背景情况:
- 口腔内镜肌切除术 (POEM) 是对食道运动障碍的领先的微创治疗方法.
- 对不同机构的POEM结果进行比较对于标准化护理至关重要.
研究的目的:
- 在两个大学中心之间比较POEM的疗效和安全性.
- 评估抗生素预防对POEM程序中不良事件的影响.
主要方法:
- 在2020年9月至2022年12月期间,对55名接受POEM治疗的患者进行了回顾性比较研究.
- 包括来自比利时利日和法国贝桑松大学医院的患者.
- 临床成功被定义为术后Eckardt得分≤3.
主要成果:
- 在87.3%的患者中诊断出阿哈拉西亚;12.7%的患者有其他食道运动障碍.
- 这两个中心都实现了高临床成功率 (总体93.2%,得分≤3).
- 副作用较低且可比;抗生素预防没有影响传染性并发症的发生率.
结论:
- 在不同大学中心,POEM的疗效和安全性均可比较.
- 这项研究强化了POEM作为安全有效的治疗选择.
- 没有发现抗生素预防会影响POEM后传染性不良事件的发生率.
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