在试管婴儿周期中,慢性子宫内膜炎妇女的孕期准备
Alla V Boychuk1, Natalia V Kotsabyn2, Julia B Yakymchuk1
1TERNOPIL NATIONAL MEDICAL UNIVERSITY NAMED AFTER I. YA. GORBACHEVSKY, TERNOPIL, UKRAINE.
概括
富血小板血 (PRP) 注射改善了慢性子宫内膜炎妇女的活产率. 这种治疗增强了子宫内膜的准备,减少了妊娠损失,并增加了生育成功率.
科学领域:
- 生殖医学 生殖医学
- 妇科 妇科 妇科 妇科
- 不孕症治疗 不孕症治疗
背景情况:
- 慢性子宫内膜炎 (CE) 是导致流产的重要原因,特别是在体外受精 (IVF) 后.
- 有效的孕前准备对于管理与CE相关的不孕症至关重要.
研究的目的:
- 为了改善慢性子宫内膜炎妇女的孕前准备.
- 通过考虑子宫内膜状况,开发个性化的方法来克服不孕症.
主要方法:
- 一项涉及90名患有慢性子宫内膜炎和解剖学正常子宫的女性 (年龄28-38岁) 的研究.
- 第一组 (n=45) 接受了CE的常规治疗.
- 第二组 (n=45) 通过自主血小板丰富血 (PRP) 的子宫内膜注射接受孕前准备.
主要成果:
- 生物化学怀孕率在I组为44.4%,在II组为62.2%.
- 在一年内恢复生育能力在PRP组 (51.1%) 比传统组 (40.0%) 更高.
- 活产率在II组 (42.2%) 与I组 (20.0%) 相比显著更高,增加了两倍.
- 与传统组 (17.8%) 相比,PRP组的早期怀孕损失减少了一半 (8.9%).
结论:
- 在患有慢性子宫内膜炎的患者中,子宫内膜下PRP注射是准备子宫内膜进行胚胎移植的有效方法.
- 这种方法可以显著增加活产率,并减少患有CE的妇女的怀孕流产.
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