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患有MIS-C的儿科患者的心脏功能使用斑点跟踪和常规心声学:一个纵向的单中心研究

Mohammad Reza Sabri¹, Alireza Ahmadi¹, Mahdieh Saviz²

¹Pediatric Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.

Pediatric cardiology

|March 3, 2024

概括

斑点跟踪心声学 (STE) 检测多系统炎症综合征 (MIS-C) 的儿童的亚临床心脏损伤. 这种先进的成像揭示了常规方法错过的微妙心肌功能障碍,有助于早期诊断和管理MIS-C心血管并发症.

科学领域:

儿童心脏病学儿童心脏病学
心血管成像 - 心血管成像
传染性疾病传染性疾病

背景情况:

儿童多系统炎症综合征 (MIS-C) 经常涉及COVID-19后的心血管并发症.
传统的胸前心电回声学 (TTE) 提供了基本的评估,但斑点跟踪心电回声学 (STE) 提供了优越的灵敏度来评估心脏功能.

研究的目的:

在使用STE诊断出MIS-C的儿科患者中纵向评估心脏功能.
为了比较MIS-C患者和健康对照之间的STE衍生的心脏参数.

主要方法:

一项涉及35名儿科MIS-C患者 (平均年龄5.1岁) 的纵向研究,在诊断时和两个月后通过STE进行评估.
与29名年龄和性别匹配的健康儿童进行了比较.
排除患有影响应变测量的并发病症的患者.

主要成果:

在MIS-C患者和对照人群之间观察到区域性心肌菌株的显著差异.
全球纵向应变 (GLS) 和应变率在MIS-C患者中较低,20%的患者表现出异常的GLS,尽管LVEF正常.
所有患者都表现出降低的细分菌株,表明广泛的亚临床心肌损伤.

结论:

对于检测MIS-C中的心脏参与,STE比传统心声回声更为敏感.
在MIS-C的急性和后急性阶段,STE显示出亚临床心肌损伤,即使LVEF被保留.

关键词:

在 COVID-19 疫情中,心脏功能测试试验的心脏功能测试试验心声回声扫描 (Echocardiography) 是一种心声回声扫描.儿童多系统炎症综合征

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