在中风后中发作复发的结果和预测因素,是一项回顾性医院研究
Erum Shariff1, Saima Nazish1, Rizwana Shahid1
1Department of Neurology, College of medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Clinical neurology and neurosurgery
|March 3, 2024
概括
女性性别是复发性中风后发作 (PSS) 的唯一独立预测因素. 复发与较旧的抗发作药物 (ASM) 和特定的EEG发现有关,影响功能结果.
科学领域:
- 神经学 神经学
- 临床神经科学 临床神经科学
- 发病学 (Epileptology) 是一个专业的学科.
背景情况:
- 脑卒中后发作 (PSS) 是一种已知的并发症,增加了发病率和死亡率.
- 对于最初PSS的临床特征,治疗和复发率的了解有限.
研究的目的:
- 为了确定第一个PSS后复发性发作的风险因素.
- 评估复发性PSS对功能结果和死亡率的影响.
主要方法:
- 电脑电图 (EEG) 监测至少24个月后的第一个PSS.
- 考克斯比例危险模型用于确定PSSR的预测因素.
- 卡普兰-梅尔分析用于累积复发延迟估计.
主要成果:
- 在36.8%的患者中观察到发作复发.
- 与PSSR的显著关联包括女性性别,年长的ASM,EEG上的焦点慢波活动,直肠形异常,状态和严重残疾.
- 女性性别是唯一独立的预测因素 (HR=3.28).
结论:
- 抗发作药物类型,EEG发现和发作类型显著影响PSSR.
- 女性性别是PSSR的唯一独立预测因素.
- 复发性PSS与显著的功能衰退有关.
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