描述患有慢性疾病的儿童的能量消耗:一个系统性审查
Bethany Luo1, Zoe E Davidson2, Katie O'Brien1
1Department of Nutrition, Dietetics and Foods, Monash University, Melbourne, Victoria, Australia.
Advances in nutrition (Bethesda, Md.)
|March 3, 2024
概括
患有慢性疾病的儿童的能量消耗对生长至关重要. 这次审查发现,关于总能耗 (TEE) 和静止能耗 (REE) 测量的变化数据有限,突出了研究缺陷.
科学领域:
- 儿童营养和新陈代谢
- 慢性疾病管理 慢性疾病管理
- 人体生理学 人体生理学
背景情况:
- 精确评估能源消耗对于管理儿童慢性疾病中生长和代谢平衡至关重要.
- 关于患有慢性疾病的儿童能量消耗的现有文献是广泛的,但需要综合来确定研究重点.
研究的目的:
- 系统地审查和描述有关慢性疾病儿童 (≤18岁) 休息能量消耗 (REE) 和总能量消耗 (TEE) 的现有文献.
- 为了评估使用的方法,主要用于REE的间接热量计 (IC) 和用于TEE的双标记水 (DLW).
- 确定这个领域未来研究的差距和机会.
主要方法:
- 在主要数据库 (OVID Medline,Embase,CINAHL Plus,Cochrane,Scopus) 进行了全面的文献搜索,截至2023年7月.
- 纳入标准集中在使用IC或DLW测量慢性疾病儿童的REE或TEE的研究上,不包括早产婴儿,急性病人和ICU患者.
- 数据提取包括能源消耗类型 (REE,TEE),疾病分层和与健康对照进行比较.
主要成果:
- 在24种慢性疾病中,共确定了271项研究,其中超过60%的研究发表于十多年前,样本大小小小.
- 大多数研究重点是REE (82%) 而不是TEE (8%),很少有人同时研究两者.
- 与健康对照人群相比,在不同慢性疾病组内和不同组之间观察到能量消耗水平的显著变化. 创建了18个预测方程,但研究质量往往受到报告质量不佳的限制.
结论:
- 目前关于儿科慢性病的能量消耗的文献虽然大量,但揭示了数据数量和质量的严重局限性,特别是TEE.
- 需要国际合作和标准化,强大的测量协议来开发可靠的预测能源方程.
- 更新的证据对于指导临床实践和支持慢性疾病儿童新兴疾病修饰疗法至关重要.
相关概念视频
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
2.5K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
Medical History
2.5K
Chronic Obstructive Pulmonary Disease-V: Management
2.5K
Managing Chronic Obstructive Pulmonary Disease (COPD) involves a multifaceted approach to reduce symptoms, prevent exacerbations, improve overall health status, and slow disease progression. Key strategies include lifestyle modifications, pharmacotherapy, supportive therapies, and, in some cases, surgery. Here is an overview of the primary COPD management strategies:
Smoking Cessation
Smoking Cessation
2.5K
Chronic Obstructive Pulmonary Disease-II: Pathophysiology
2.8K
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
Chronic Inflammation
2.8K
Chronic Obstructive Pulmonary Disease
1.2K
COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
1.2K
Chronic Obstructive Pulmonary Disease-I: Introduction
2.8K
Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
2.8K
Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
2.8K
Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
2.8K


