牛皮皮炎,儿童牛皮和亚托皮性皮炎早期形式的常见表型:一项前性多中心研究
Alexandre Docampo-Simón1,2, Isabel Belinchón1,2,3, María J Sánchez-Pujol1,2
1Dermatology Department, Hospital General Universitario Dr Balmis, Alicante, Spain.
International journal of dermatology
|March 3, 2024
概括
儿童的牛皮皮炎 (PD) 通常会发展为牛皮 (Ps) 或亚托皮炎 (AD). 长期跟踪对于准确诊断这些慢性免疫介导疾病至关重要.
科学领域:
- 儿科皮肤病学 儿科皮肤病学
- 免疫皮肤学 免疫皮肤学
- 慢性病的进展 慢性病的进展
背景情况:
- 牛皮 (Ps) 和亚托皮炎 (AD) 是一种慢性,免疫媒介疾病.
- 牛皮皮炎 (PD) 是一种重叠的疾病,具有Ps和AD的特征,主要在儿童中见到.
- 儿童群体中PD的自然史和预测因素尚未得到充分理解.
研究的目的:
- 为了确定儿科牛皮皮炎 (PD) 演变为牛皮 (Ps) 或亚托邦性皮炎 (AD) 的速度.
- 确定可能预测患有PD的儿童疾病进展的临床和流行病学因素.
主要方法:
- 进行了一项前性的多中心队列研究.
- 包括在2018年1月至2020年12月期间被诊断患有PD的24名儿童.
- 收集了临床和流行病学数据;儿童皮肤科医生评估了疾病的演变.
主要成果:
- 在31个月的中位数随访后,83.3%的PD儿童发展为Ps (44.4%) 或AD (38.9%).
- 诊断时年轻的年龄和牛皮家族病史与AD的进展有关.
- 进展为Ps或AD的儿童与持久PD的儿童相比,随访时间更长.
结论:
- 显著的大多数儿科牛皮皮炎 (PD) 病例会随着时间的推移演变成牛皮 (Ps) 或亚型皮炎 (AD).
- 长期临床监测对于准确诊断和治疗PD儿童至关重要.
- 识别预测因素可以帮助预测疾病的发展轨迹和量身定制患者护理.
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