在患有自闭症谱系障碍和注意力缺陷/多动障碍的青少年中,常见而明显的皮质厚度变化
Wanfang You1,2,3, Qian Li1,2, Lizhou Chen1,2
1Department of Radiology and Huaxi MR Research Center (HMRRC), Functional and Molecular Lmaging Key Laboratory of Sichuan Province, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, People's Republic of China.
BMC medicine
|March 3, 2024
概括
自闭症谱系障碍 (ASD) 和注意力缺陷/多动性障碍 (ADHD) 在默认模式网络 (DMN) 中共享了减少的关节 (TPJ) 皮层厚度 (CTh). 注意网络中的明显的CTh模式为神经发育障碍的差异提供了洞察力.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 遗传学 是一个遗传学.
背景情况:
- 自闭症谱系障碍 (ASD) 和注意力缺陷/多动障碍 (ADHD) 是神经发育障碍,具有重叠的遗传和行为特征.
- 之前的研究表明,在ASD和ADHD中,皮层厚度 (CTh) 的改变是分别存在的,但共同的和独特的模式仍然不清楚.
结论:
- 在DMN中共享降低TPJ CTh表明ASD和ADHD中的重叠神经生物学特征.
- 在注意力网络 (背部和腹部) 中明显的CTh变化为每种疾病中的特定注意力缺陷提供了洞察力.
- 在ASD中SPL变化可能与生物运动处理有关,而ADHD中的感觉运动异常可能导致行为控制问题.
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