相关实验视频

Updated: Jul 1, 2025

Author Spotlight: Visualizing Single-Stranded DNA During DNA Repair for Therapeutic Insights
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Author Spotlight: Visualizing Single-Stranded DNA During DNA Repair for Therapeutic Insights

Published on: December 22, 2023

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CDK9-55指导亚纳酶促进复合体/循环体 (APC/C) 在选择DNA修复途径的选择过程中

Luigi Alfano1, Carmelina Antonella Iannuzzi2, Daniela Barone2

  • 1Cell Biology and Biotherapy Unit, Istituto Nazionale Tumori-Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS)-Fondazione G. Pascale, Napoli, Italy. l.alfano@istitutotumori.na.it.

Oncogene
|March 3, 2024
PubMed
概括

循环素依赖性激酶9 (CDK9-55) 影响DNA修复路径的选择. 它与CDC23的相互作用会损害同源重组 (HR) 并促进易发生错误的非同源末端连接 (NHEJ),影响癌症治疗策略.

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