评估光学连贯性断层扫描 血管扫描 在帕斯平面炎和多发性硬化症相关的中介性水道炎中缓解的发现
Berru Yargi-Ozkocak1, Cigdem Altan1, Burcu Kemer-Atik1
1Beyoglu Eye Training and Research Hospital, University of Health Sciences Turkey, Istanbul, Turkey.
Current eye research
|March 4, 2024
概括
与对照组相比,光学连贯性断层扫描血管学 (OCT-A) 显示,与对照组相比,帕斯平原炎中介性脑膜炎 (PP-IU) 和多发性硬化症相关的中介性脑膜炎 (MS-IU) 患者的表面毛细血管 (SCP) 血管密度降低. 在PP-IU中监测状血管区域 (FAZ) 可能表明慢性.
科学领域:
- 眼科医生 眼科 眼科
- 神经眼科神经眼科
- 医疗成像医学成像
背景情况:
- 帕斯平原炎中级脑膜炎 (PP-IU) 和多发性硬化症相关的中级脑膜炎 (MS-IU) 是一种炎症性眼睛疾病.
- 在缓解期间了解这些条件下的微血管结构对于评估疾病活性和病原性至关重要.
研究的目的:
- 评估和比较PP-IU和MS-IU患者的眼睛微血管在缓解期间使用光学连贯断层扫描血管学 (OCT-A) 评估和比较.
- 评估PP-IU和MS-IU之间血管参数的潜在差异及其与疾病特征的相关性.
主要方法:
- 一个单中心的描述性病例对照研究招募了经过缓解的PP-IU或MS-IU的成年患者,以及年龄和性别匹配的健康对照 (HC).
- 光学连贯性断层扫描血管学 (OCT-A) 用于分析状血管区域 (FAZ) 和表面和深层毛细管 (SCP/DCP) 和胆管毛细管的血管密度.
- 记录了人口统计,临床和眼部发现,包括最佳校正视敏度 (BCVA) 和囊性黄斑胀 (CME).
主要成果:
- 与HC组相比,在PP-IU和MS-IU组中观察到SCP的血管密度降低 (p < .05).
- 在PP-IU和MS-IU组之间没有发现OCT-A参数的显著差异.
- 尿道炎的持续时间与PP-IU组的FAZ区域扩大相关 (p = .039).
结论:
- OCT-A可能无法区分PP-IU和MS-IU,这表明潜在的共享病原体.
- 降低SCP血管密度表明缓解期间这两种情况的微血管变化.
- 在PP-IU中监测FAZ区域对于评估疾病慢性是有价值的.
更多相关视频
相关概念视频
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
Imaging Studies VII: Vascular Imaging
DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...


