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表面修饰策略,以提高聚合物材料的血液相容性:综合性审查

Abhishek Bhattacharjee1, Aniruddha Vijay Savargaonkar2, Muhammad Tahir3

  • 1School of Advanced Material Discovery, Colorado State University Fort Collins CO 80523 USA.

RSC advances
|March 4, 2024
PubMed
概括

聚合物生物材料的表面修饰对于血红相容性至关重要. 本综述探讨了控制植入物表面血凝的策略,平衡了伤口愈合的好处与阻塞的风险.

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Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...
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