口腔HPV相关的发育不良:小囊细胞发育不良是一个单独的实体吗?
Gabriela Anaya-Saavedra1, Marcela Vázquez-Garduño1
1Oral Pathology and Medicine Postgraduate Program, Health Care Department, Metropolitan Autonomous University, Mexico City, Mexico.
Frontiers in oral health
|March 4, 2024
概括
诊断与高风险的人类乳头瘤病毒 (HPV) 感染相关的口腔上皮质松症需要标准化术语. 一致的命名有助于准确的诊断,并改善HPV-口腔发育不良的患者的结果.
科学领域:
- 口腔病理学 口腔病理学
- 病毒学 病毒学
- 在瘤学瘤学.
背景情况:
- 与高风险的人类乳头瘤病毒 (HPV) 感染相关的口腔表皮质变形症是使用各种术语来描述的,包括口腔Bowenoid病变和与HPV相关的表皮内瘤.
- 组织病理学特征,如阿波性角质细胞,卡里奥雷克西斯和线粒体数字,与病毒转录状态和负载有关.
研究的目的:
- 为了解决HPV-口腔表皮发育不良症在HPV口腔表皮发育不良症中的术语不一致导致的诊断混乱.
- 强调需要采用统一的诊断方法来准确和早期检测HPV口腔发育不良.
主要方法:
- 关于口腔上皮质质变形和HPV感染的现有文献的综述.
- 分析与病毒载荷和转录状态相关的组织病理特征.
主要成果:
- 与HPV相关的口腔病变的术语不一致会造成诊断挑战.
- 特定的细胞特征与病毒活性相关,影响诊断解释.
结论:
- 针对HPV-口腔表皮质变形的标准化命名对医学和研究界至关重要.
- 标准化将促进准确的诊断,及时干预和改善患者的治疗结果,特别是在高危人群中.
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