来自哥伦比亚西南部一个高度复杂的医院的Viperidae蛇中毒
Valeria Erazo-Martínez1, Iván Posso-Osorio2, Ingrid Ruiz-Ordoñez1
1Fundación Valle del Lili, Centro de Investigaciones Clínicas, Cali, Colombia.
Heliyon
|March 4, 2024
概括
哥伦比亚的毒蛇毒害导致严重的疼痛和凝血病. 及时的多价抗毒治疗是有效的,但延迟治疗会增加并发症的风险.
科学领域:
- 医学毒理学医学毒理学
- 蛇咬的流行病学 蛇咬的流行病学
- 临床热带医学临床热带医学
背景情况:
- 蛇毒在哥伦比亚西南部是一个重大的公共卫生挑战,因为哥伦比亚的疾病和死亡率很高.
- 毒蛇蛇咬伤在该地区是一个重大问题,需要详细了解它们的临床影响.
研究的目的:
- 在哥伦比亚西南部的一家大型医院治疗的Viperidae蛇毒的临床表现和结果的特征.
- 评估多价抗毒药在治疗蛇咬病例中的有效性.
主要方法:
- 一项横截面研究分析了2001年至2020年期间为Viperidae蛇毒毒治疗的28名患者的数据.
- 收集的数据包括患者人口统计,咬伤位置,临床症状,实验室发现 (凝血病),抗毒治疗细节和并发症.
主要成果:
- 该研究包括28名患者,主要是男性,咬伤最常见的是上肢. 常见的症状是疼痛和,其中46%的人患有凝血病.
- 多价抗毒剂给了71%的患者,门到针的中位时间为37.5分钟. 64%的患者需要进入重症监护室.
- 这些并发症包括血清疾病 (11%),感染 (25%),手术干预 (14%),隔间综合征 (3%) 和一次死亡 (3%).
结论:
- 局部症状和凝血病在Viperidae蛇毒中很常见.
- 多价抗毒药在控制蛇毒中表现出有效性.
- 延迟医疗护理与严重程度和并发症的增加密切相关.
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