患有胸前大动脉内血管假体的患者的血液流动效应
Juan P Tello1, Juan C Velez1, Alberto Cadena2
1Universidad del Norte, Km. 5 Via Puerto Colombia, Barranquilla, Colombia.
Heliyon
|March 4, 2024
概括
内血管假肢显著扰乱大动脉血流,改变血液动力学,并可能导致临床并发症. 这项研究使用计算流体动力学来分析带假肢和没有假肢的患者的流动行为.
科学领域:
- 生物医学工程 生物医学工程
- 心血管生理学心血管生理学
- 医学成像和模拟技术
背景情况:
- 大动脉血动力学对于血管健康至关重要.
- 内血管假肢可以改变正常的血液流动模式.
- 了解这些变化是预防并发症的关键.
研究的目的:
- 分析老年患者大动脉中的血液动力学现象.
- 为了研究内血管假肢对血液流动行为的影响.
- 为了比较有正规的大动脉几何形状的患者与假肢患者的流动动力学.
主要方法:
- 使用计算流体动力学 (CFD) 进行分析.
- 测量速度,压力和墙面剪切应力 (WSS).
- 在心脏周期期间分析特定截面 (CS1,CS2) 的数据.
主要成果:
- 正规的大动脉几何学显示出可预测的流体动力学.
- 患者II的内置假肢显著扰乱了脉动性流动,特别是在CS2附近.
- 患者II表现出不规则的流体行为,改变速度,压力差异和低WSS由于假肢.
结论:
- 内血管假肢显著影响大动脉血流和血液动力学.
- 由假肢引起的流动障碍可能导致血管变化和临床并发症.
- 假肢-内皮相互作用和几何变化有助于流动中断.
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