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Updated: Jul 1, 2025

Human Pluripotent Stem Cell Culture on Polyvinyl Alcohol-Co-Itaconic Acid Hydrogels with Varying Stiffness Under Xeno-Free Conditions
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Human Pluripotent Stem Cell Culture on Polyvinyl Alcohol-Co-Itaconic Acid Hydrogels with Varying Stiffness Under Xeno-Free Conditions

Published on: February 3, 2018

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作为能量代谢调节器的细胞外基质刚性驱动介质干细胞的骨质分化

Jing Na1, Zhijie Yang1, Qiusheng Shi1

  • 1Key Laboratory of Biomechanics and Mechanobiology (Beihang University), Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing, 100083, China.

Bioactive materials
|March 4, 2024
PubMed
概括

刚性生物材料通过增强能量代谢和线粒体功能来促进干细胞分化. 这项研究强调了YES相关蛋白 (YAP) 在整合机械线索和代谢信号的作用,用于骨组织工程.

关键词:
细胞力学 细胞力学矩阵的刚度 矩阵的刚度代谢调节 代谢调节 代谢调节干细胞的命运 干细胞的命运哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈

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