Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Depressive symptoms and risk of incident activities of daily living disability among older adults with symptomatic arthritis.

Frontiers in medicine·2026
Same author

m<sup>1</sup>A Modification: An Emerging Epitranscriptomic Regulator of Stem Cell Fate.

Stem cell reviews and reports·2026
Same author

Research hotspots and prospects on the correlation between subchondral bone and stem cells: bibliometrics and visual analysis.

Frontiers in surgery·2026
Same author

Clinical Retrospective Study on Superior Capsular Reconstruction Using Autologous Fascia Lata Combined With LARS Ligament for Massive Irreparable Rotator Cuff Tears.

Orthopaedic surgery·2026
Same author

The relationship between arthritis and mild cognitive impairment in different obese metabolic heterogeneity populations-the mediating role of depression.

Frontiers in nutrition·2026
Same author

Transverse inter-metacarpal K-wire with Nice-knot augmentation versus mini-plate fixation for second-fifth metacarpal shaft fractures: a single-center retrospective cohort study.

Archives of orthopaedic and trauma surgery·2025

相关实验视频

Updated: Jul 1, 2025

Author Spotlight: Improving the Production of Self-Assembling Fibers and Peptide Hydrogels for Superior Biocompatibility
05:24

Author Spotlight: Improving the Production of Self-Assembling Fibers and Peptide Hydrogels for Superior Biocompatibility

Published on: September 6, 2024

1.2K

使用酸水凝进行快速血液静止的实验研究.

Linru Zeng1, Gan Luo1, Zhenshuang Yue1

  • 1Department of Orthopedics, Hangzhou Xiaoshan Traditional Chinese Medical Hospital, Hangzhou 311201, P. R. China.

ACS omega
|March 4, 2024
PubMed
概括
此摘要是机器生成的。

新的化物纳米纤维迅速停止出血并促进愈合. 这些自组装生物材料为创伤和手术出血提供了有前途的静血剂,性能优于商业产品.

更多相关视频

Microwave-assisted Functionalization of Polyethylene glycol and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation
15:33

Microwave-assisted Functionalization of Polyethylene glycol and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation

Published on: October 29, 2013

28.9K
The Synthesis of RGD-functionalized Hydrogels as a Tool for Therapeutic Applications
09:30

The Synthesis of RGD-functionalized Hydrogels as a Tool for Therapeutic Applications

Published on: October 7, 2016

11.3K

相关实验视频

Last Updated: Jul 1, 2025

Author Spotlight: Improving the Production of Self-Assembling Fibers and Peptide Hydrogels for Superior Biocompatibility
05:24

Author Spotlight: Improving the Production of Self-Assembling Fibers and Peptide Hydrogels for Superior Biocompatibility

Published on: September 6, 2024

1.2K
Microwave-assisted Functionalization of Polyethylene glycol and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation
15:33

Microwave-assisted Functionalization of Polyethylene glycol and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation

Published on: October 29, 2013

28.9K
The Synthesis of RGD-functionalized Hydrogels as a Tool for Therapeutic Applications
09:30

The Synthesis of RGD-functionalized Hydrogels as a Tool for Therapeutic Applications

Published on: October 7, 2016

11.3K

科学领域:

  • 生物材料科学 生物材料科学
  • 纳米技术纳米技术
  • 再生医学是一种再生医学.

背景情况:

  • 在民用和军事环境中,不受控制的出血会造成严重的死亡风险.
  • 自组装纳米纤维显示出快速血液静止,生物相容性和伤口愈合的潜力.

研究的目的:

  • 设计和表征用于血液静止的新纳米纤维.
  • 为了评估它们的自我组装,生物相容性和体内静血疗效.

主要方法:

  • 体设计包含类似鱼网和RGD序列.
  • 使用传输电子显微镜,扫描电子显微镜,圆形二元化和里埃变换红外光谱学进行表征.
  • 实验室细胞增殖试验和实验室血液静止试验用于大鼠模型.

主要成果:

  • 可以自组装成具有纳米网络和纳米纤维结构的稳定水凝.
  • 证明了 β-sheet 主导的二次结构,支持 β-turn 和 α-helix.
  • 促进纤维细胞和肝细胞的增殖,并显示出显著的静血作用,比商业药物更快38秒的静血.
  • 有效促进肝脏缺陷的快速修复.

结论:

  • 设计的化物纳米纤维有效地促进血静和组织修复.
  • 这种自组装策略为严重出血,特别是肝脏出血提供了有前途的临床治疗方法.
  • 进一步开发基作为血液静止剂是有必要的.