肝炎C可归因的医疗保健成本和移民中的死亡率:基于人口的匹配队列研究
Aysegul Erman1,2, Yeva Sahakyan1, Karl Everett2
1Toronto Health Economics and Technology Assessment Collaborative (THETA), University Health Network, Toronto, ON, Canada.
Canadian journal of gastroenterology & hepatology
|March 4, 2024
概括
慢性型肝炎 (CHC) 显著增加了安大略省移民的死亡率和医疗保健成本. 这项研究量化了经济负担,帮助风险人群的HCV消除策略.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 卫生经济学 卫生经济学
背景情况:
- 移民人口中慢性型肝炎 (CHC) 对经济影响的数据有限.
- 估计移民中可归因于心血管疾病的死亡率和医疗保健成本的负担对于有针对性的干预至关重要.
研究的目的:
- 估计加拿大安大略省移民中与CHC相关的死亡率和医疗保健支出.
- 提供支持计划和实施型肝炎病毒 (HCV) 消除工作的数据.
主要方法:
- 基于人口的匹配队列研究使用链接的卫生行政数据进行.
- 根据人口统计和倾向得分,被诊断患有CHC的移民与未暴露的移民进行了1:1匹配.
- 医疗保健费用是从付款人的角度计算出来的,采用阶段性治疗方法,调整为生存.
主要成果:
- 一组5575名感染CHC的移民与对照组进行了匹配.
- 在CHC组中,死亡率明显较高 (10.5%与15年后的3.5%相比;RR=2.9).
- 经过生存调整后,平均15年净医疗费用达到每人90,448美元,在不同疾病阶段的医疗费用相当高.
结论:
- 与未暴露的同行相比,患有CHC的移民经历了较高的死亡率和更高的医疗保健费用.
- 这些发现强调了针对安大略省移民社区的专注HCV消除策略的必要性.
- 量化经济负担对于公共卫生倡议的资源配置至关重要.
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