相关实验视频
Updated: May 6, 2026

12:23
Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
10.5K
在POEMS综合征的calciphylaxis:案例报告
Danica Novacic1, Thomas Uldrick2, Alina Dulau-Florea3
1Undiagnosed Diseases Program, National Institutes of Health (NIH) Common Fund, Office of the Director, NIH, Bethesda, MD, USA.
Rare (Amsterdam, Netherlands)
|March 4, 2024
概括
卡尔西菲拉克西,POEMS综合征的罕见并发症 (多重神经病变,有机巨变,内分泌病变,单克隆血细胞疾病,皮肤变化),可以在完整的综合征诊断之前. 在POEMS患者中,早期识别和治疗形症至关重要.
科学领域:
- 血管医学 血管医学
- 血液学 血液学 血液学
- 皮肤病学 皮肤病学
背景情况:
- 诗人综合征是一种罕见的多系统性疾病.
- 石灰症是一种严重的微血管并发症,其特点是血管化和皮肤亡.
- 卡尔西菲拉克西是POEMS综合征的一个不常见的表现.
研究的目的:
- 报告一个POEMS综合征的病例,其中calciphylaxis是最初呈现的表现.
- 为了突出化症可能在POEMS综合征的诊断之前存在的可能性.
- 讨论这个罕见的演示的管理和结果.
主要方法:
- 一个患有广泛的石灰症的患者的病例报告,随后诊断出POEMS综合征.
- 诊断工作包括皮肤活检用于化和骨髓活检用于血细胞评估.
- 治疗包括支持性护理,用于化和化学疗法,用于POEMS综合征.
主要成果:
- 患者出现了严重的石灰症,包括死性皮肤病变和急性损伤.
- 根据临床标准和骨髓发现的兰巴链受限血细胞,诊断出POEMS综合征.
- 多模式治疗导致了化症和POEMS综合征表现的改善.
结论:
- 卡尔西菲拉克斯可以是POEMS综合征的突出和早期特征.
- 识别状症可能会促使更早地诊断出潜在的POEMS综合征.
- 对于患者的治疗结果来说,和POEMS综合征的综合管理至关重要.
相关概念视频
Pericarditis II: Clinical Features and Diagnostic Tests
638
Pericarditis is distinguished by inflammation of the pericardium, the fibrous sac that encases the heart. It can be acute, lasting less than six weeks, or chronic, persisting for over three months. Understanding its clinical manifestations and diagnostic findings is crucial for timely and effective management.Clinical ManifestationsWhile pericarditis can be asymptomatic, it usually presents with characteristic symptoms such as:Chest Pain: The most characteristic symptom of pericarditis is chest...
638
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
961
The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
961
Nephrotic Syndrome I : Introduction
1.2K
Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
1.2K
Nephrotic Syndrome III : Nursing Management
561
Nursing management for nephrotic syndrome adapts as the disease progresses, with strategies evolving to address advancing symptoms and complications.Early-Stage Management In the early stages, nursing interventions for nephrotic syndrome resemble those used in managing acute glomerulonephritis, focusing on symptom monitoring, fluid balance, and managing mild to moderate edema.Vital Signs: Regularly monitor blood pressure, pulse, respiratory rate, and temperature to promptly identify...
561
Chronic Kidney Disease II: Clinical Manifestations
1.1K
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
1.1K
Graves Disease II: Pathophysiology
59
Graves’ disease is an autoimmune disorder characterized by the production of thyroid-stimulating immunoglobulins (TSI) that activate TSH receptors, leading to excessive synthesis and release of thyroid hormones (T3 and T4) and resulting in hyperthyroidism.Among all causes of hyperthyroidism, Graves’ disease is the most common and can happen at any age, though it is more frequent in women. It produces a hypermetabolic state with features such as weight loss, tachycardia, tremor,...
59

