机械通风器共享系统的开发和评估.
Satyanarayana Achanta1, Michael A Gentile1, Neil R Euliano2
1Department of Anesthesiology, Duke University School of Medicine, Durham, NC, United States.
Frontiers in medicine
|March 4, 2024
概括
开发了一种新的呼吸器共享系统 (VSS) 和远程监控系统 (VMS),用于在重症监护期间为多名患者提供呼吸. 这些系统准确地提供个性化的机械通风,在实验室和动物研究中被证明是有效的.
科学领域:
- 生物医学工程 生物医学工程
- 临界护理医学 临界护理医学
- 呼吸系统疗法 呼吸系统疗法
背景情况:
- 随着COVID-19的流行,机械呼吸机的严重短缺问题得到了强调.
- 研究了用于机械通风的替代策略,包括设备共享,以满足增加的需求.
- 显而易见的是,需要系统来个性化患者的通风,并使远程监控成为可能.
研究的目的:
- 开发和评估使用临床上可用的组件进行多个患者同时通风的通风器共享系统 (VSS).
- 开发和评估用于远程监测肺机械的呼吸机监控系统 (VMS).
- 确定VSS和VMS在提供个性化机械通风方面的可行性和有效性.
主要方法:
- 开发了使用现成组件的通风器共享系统 (VSS) 和通风器监控系统 (VMS).
- 在实验台测试中评估VSS和VMS,其中两个试验肺连接到单个呼吸机.
- 在模拟正常和受损肺功能的转化猪模型中评估系统性能.
主要成果:
- 基板测试表明VSS和VMS在提供设置的通风参数方面具有高精度和准确性.
- 动物研究证实,VSS和VMS在临床上可接受的范围内成功提供了个性化的机械通风.
- 在动物模型中,在目标和测量通风值之间没有发现统计学上显著的差异.
结论:
- 该VSS有效地通风了多个试验肺或具有不同肺状况的动物.
- VMS准确地显示了通风设置,参数和报警.
- 这些系统在流行病或大规模伤亡事件期间为重症监护室通风提供了可扩展的解决方案,利用易于获得和3D打印的组件.
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