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在实施妊娠普遍查后,检测和管理C型肝炎病毒

Sarah Boudova¹, Danielle M Tholey², Elizabeth Ferries-Rowe¹

¹Department of Obstetrics and Gynecology Indiana University School of Medicine, Indianapolis, IN (Drs Boudova and Ferries-Rowe).

AJOG global reports

|March 4, 2024

概括

在怀孕期间,普遍的查C型肝炎病毒 (HCV) 显著增加了鉴定率. 然而,产后治疗和婴儿查仍然很低,静脉注射药物使用与治疗转诊减少有关.

科学领域:

肝病学肝病学是一种肝病学.
公共卫生公共卫生
孕产妇和胎儿医学孕产妇和胎儿医学

背景情况:

型肝炎病毒 (HCV) 鉴定对公共卫生有重大影响.
最近的指导方针建议在怀孕期间进行普遍的HCV查,因为患病率上升和有效的治疗方法.
关于普遍查对病例识别和管理的影响的数据有限.

研究的目的:

评估普遍HCV查对孕妇患者的影响.
为了比较HCV在政策实施之前和之后的流行率.
评估产后管理,包括转诊和治疗率,以及婴儿查.

主要方法:

在普遍查之前 (2018年7月至2020年6月) 和之后 (2020年7月至2021年12月) 的分娩回顾性队列研究.
从电子医疗记录中提取的关于HCV/HIV状态,查和药物使用的数据.
对风险因素分析的子集进行问卷调查.

主要成果:

查HCV的比率从5.78%增加到77.25% (P<.01).
冠状病毒感染率保持稳定 (0.78%对0.81%,P=.88).
产后治疗转诊率为67.61%,其中18.75%接受治疗;静脉注射药物使用降低了转诊率 (OR,0.14).
在符合条件的婴儿中,婴儿查率为15.38%.

结论:

全球查显著提高了孕妇的HCV鉴定.
产后治疗和婴儿查率仍然低于最佳水平.
改善与护理的联系对于增加产后治疗率至关重要.

关键词:

在HCV病毒感染的过程中,直接作用的抗病毒药物.在C型肝炎病毒的感染中,静脉注射使用毒品.怀孕怀孕怀孕怀孕怀孕全民查是普遍的查.垂直传输的垂直传输方式

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