普罗波,德斯弗和脊柱麻醉在腰椎椎间盘的手术期间对眼内压力的影响:一项随机对照研究
1Department of Anesthesiology and Reanimation, Faculty of Medicine, Giresun University, Giresun, Turkey. elvan.yilmaz@giresun.edu.tr.
European review for medical and pharmacological sciences
|March 4, 2024
概括
总静脉注射麻醉 (propofol) 在容易脊柱手术期间增加眼内压力 (IOP),与德斯弗和脊柱麻醉相比. 挥发性麻醉 (desflurane) 和脊髓麻醉在这些患者中更安全地维持较低的内血压.
科学领域:
- 麻醉学 麻醉学
- 神经外科 神经外科
- 眼科医生 眼科 眼科
背景情况:
- 在倾斜脊柱手术期间,眼内压力 (IOP) 管理至关重要.
- 不同的麻醉技术可能会影响IOP,影响手术结果.
研究的目的:
- 为了比较全静脉麻醉 (propofol),挥发性麻醉 (desflurane) 和脊椎麻醉在易患腰椎间盘的手术期间对IOP的影响.
主要方法:
- 随机对照试验,75名患者 (ASA 1-2) 接受腰椎间盘的手术.
- 患者被随机分配到普罗波,德斯弗或脊髓麻醉组.
- 内压在五个时间点测量:基线,麻醉后,早期易感,晚期易感和后.
主要成果:
- 与德斯兰相比,在早期倾斜的位置上, пропофол麻醉导致眼内压力 (IOP) 显著增加 (p=0.001).
- 在调整后,desflurane和脊髓麻醉组显示T3 IOP明显低于propofol组.
- 糖尿病和基线内血压与更高的早期易发生内血压有关.
结论:
- 挥发性麻醉 (desflurane) 和脊髓麻醉与脊髓手术期间倾斜位置的眼内压力 (IOP) 与静脉内全麻醉 (propofol) 相比较较低.
- 建议进行进一步的基于人口的研究,以在不同患者群体中验证这些发现.
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