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Updated: Jul 1, 2025

Multimodal 3D Printing of Phantoms to Simulate Biological Tissue
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4D打印用于生物医学应用.

Arkodip Mandal1, Kaushik Chatterjee1

  • 1Department of Materials Engineering, Indian Institute of Science, Bengaluru, Karnataka 560012, India. kchatterjee@iisc.ac.in.

Journal of materials chemistry. B
|March 4, 2024
PubMed
概括
此摘要是机器生成的。

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四维 (4D) 打印使材料的可编程形状和功能变化成为可能. 这种先进的制造技术对动态组织工程,药物输送和医疗设备具有前景.

科学领域:

  • 添加剂制造 添加剂制造 添加剂制造
  • 材料科学 材料科学 材料科学
  • 生物医学工程 生物医学工程

背景情况:

  • 三维 (3D) 打印创造了静态物体,限制了动态生物系统中的应用.
  • 原生组织和先进的医疗设备需要动态,响应的功能,无法通过静态3D打印实现.

研究的目的:

  • 审查4D打印的材料,打印和后处理方面的进展.
  • 探索4D打印材料的多样化生物医学应用.
  • 确定挑战,并提出4D打印临床转化策略.

主要方法:

  • 总结材料化学的最新进展,用于刺激响应的聚合物,陶和金属.
  • 审查3D打印策略和后打印技术,以实现时间动态.
  • 分析当前和潜在的生物医学应用,包括组织工程和药物输送.

主要成果:

  • 4D打印使软材料 (水凝,聚合物,弹性体),陶和金属的时间可编程.
  • 关键应用包括先进的组织工程,可控药物递送系统,复杂的体外模型和响应性医疗设备.
  • 材料科学和印刷方法的进步推动了动态4D打印结构的实现.

结论:

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  • 4D打印通过使动态材料行为成为可能,为生物医学应用提供了变革性的潜力.
  • 克服当前的挑战需要一个应用驱动的设计方法,以获得成功的临床翻译.
  • 4D打印的广泛采用取决于持续的创新和解决实施障碍.