[267名患有埃索诺菲尔性胃肠道疾病的儿童的临床特征:多中心研究]
Chun-Lei Zhan1, Jie-Yu You, Xiao-Qin Li
1Department of Gastroenterology, Jiangxi Children's Hospital, Nanchang 330000, China (Wan S-H, Email: jeft1210@ 126. com).
概括
儿童患有异性胃肠道疾病 (EGID) 通常是轻度至中度,表现出各种症状. 治疗主要涉及饮食变化,酸性抑制和抗过敏药物,导致一般有利的预后.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 过敏和免疫学 过敏和免疫学
- 胃肠道疾病 胃肠道疾病
背景情况:
- 生性胃肠道疾病 (EGID) 是一种免疫媒介的疾病,其特征是生性胃肠道透.
- 了解EGID在儿童群体中的临床谱,诊断挑战和治疗结果对于有效管理至关重要.
- 儿科医生的有限认识可能会推迟对儿童EGID的诊断和适当干预.
研究的目的:
- 在儿科队列中全面调查EGID的临床表现,内镜和组织病理学发现,治疗策略和预后.
- 提高儿科医生对EGID的认识和认可,促进早期诊断和改善患者护理.
- 确定儿科EGID的关键临床特征和有效的治疗方法.
主要方法:
- 一项涉及267名被诊断患有EGID的儿童的前性研究从2019年1月到2022年7月在三个主要儿童医院进行.
- 收集的数据包括发病年龄,出现症状,体检结果,实验室结果,内镜观察,组织病理分析和治疗反应.
- 进行了统计分析,以评估发现的意义,包括血小板计数和严重程度组之间的差异 (P>0.05).
主要成果:
- 大多数儿科EGID病例的严重程度为轻度 (61.4%) 或中度 (35.6%),在学龄儿童中患病率更高.
- 常见的症状因年龄组而异,包括婴儿和幼儿的吐,血和血,以及较大的儿童的腹痛和吐.
- 虽然85.0%接受了酸性抑制,34.5%的饮食避免和20.9%的抗过敏药物治疗,但所有患者都显示出症状缓解,在停止治疗胃潰瘍后注意到一些复发.
结论:
- 轻度至中度的EGID在儿童中普遍存在,通常缺乏特定的内镜或组织病理学标志物.
- 关键的治疗方法包括饮食修改,酸抑制疗法和抗过敏药物,在症状解决方面表现出有效性.
- 儿童EGID的预后通常是有利的,尽管需要警胃等并发症和潜在的复发.
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